Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 132
interventional 98
Observational 30
Registry 4

Studies over Time by Start Date

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Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 42
Drug|placebo 37
Biological|placebo 8
Biological 5
Other 2
Behavioral 1
Device 1
Device|placebo 1
Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
Germany 17
United States 17
NA 10
France 8
Canada 4
India 2
Spain 2
Taiwan 2
Turkey 2
United States|Australia|Canada|Germany|Greece|Japan|Russian Federation|Spain|Taiwan|United Kingdom 2
United States|Denmark|France|Germany|Italy|Poland|Spain|Turkey 2
Argentina|Belgium|France|Germany|Poland|Romania|Spain 1
Argentina|Brazil|Canada|Chile|Dominican Republic|Guatemala|Mexico|Panama 1
Australia|Germany|Sweden 1
Belgium|France|Germany|Italy|Malaysia|Romania|South Africa|Spain|United Kingdom 1
Bulgaria 1
Canada|Germany 1
Canada|Japan|Mexico 1
China 1
Colombia 1
Germany|United Kingdom 1
Israel 1
Italy 1
Japan 1
Japan|Korea, Republic of 1
Korea, Republic of 1
Switzerland 1
Thailand 1
United Kingdom 1
United States|Argentina|Australia|Belgium|Brazil|Chile|Estonia|Finland|France|Germany|India|Israel|Italy|Japan|Lebanon|Mexico|Netherlands|Philippines|Poland|Romania|Russian Federation|Slovakia|Spain|Taiwan|Tunisia|United Kingdom|Vietnam 1
United States|Argentina|Austria|Brazil|Bulgaria|Canada|Colombia|Croatia|Czechia|Denmark|France|Germany|Greece|Guatemala|Hungary|India|Korea, Republic of|Malaysia|Oman|Peru|Poland|Puerto Rico|Russian Federation|Singapore|South Africa|Spain|Sweden|Thailand|Turkey 1
United States|Argentina|Belgium|Canada|Czechia|Denmark|France|Germany|Hungary|Japan|Netherlands|Poland|Russian Federation|Slovakia|Spain|Turkey|United Kingdom 1
United States|Argentina|Belgium|Canada|Estonia|Germany|Hungary|India|Russian Federation|Spain|Switzerland|Taiwan|Turkey 1
United States|Argentina|Canada|Japan 1
United States|Australia|Germany|New Zealand|Poland|Singapore|Switzerland|United Kingdom 1
United States|Belgium|Canada|Czechia|Hungary|Japan|Poland|Slovakia|Spain|United Kingdom 1
United States|Canada 1
United States|Canada|Germany 1
United States|Germany 1
United States|Germany|Poland 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 51
2 4
3 5
4 4
6 1
7 1
10 2
11 3
12 1
13 1
19 1
24 2
25 1
26 2
27 2
28 1
29 2
35 1
38 1
39 1
40 1
50 1
61 1
66 1
68 1
73 1
80 1
82 1
92 1
192 1
206 1

Phase

Phase Study_Count
Phase 2 30
Phase 3 29
Phase 4 18
N/A 7
Phase 1 6
Phase 1/Phase 2 3
Phase 2/Phase 3 3
Early Phase 1 2

Number of Arms

Number_of_Arms Count_of_Studies
1 20
2 39
3 17
4 9
5 2
6 3
7 1
NA 7

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 10.0 4.00000 4.00 4 5.00000 20 15.0000 10.0000
1st Qu. 12.5 31.00000 9.75 20 20.00000 25 74.0000 20.2500
Median 15.0 75.00000 19.50 36 39.00000 30 218.0000 65.5000
Mean 15.0 73.28571 18.50 32 73.66667 50 263.8276 141.7778
3rd Qu. 17.5 111.00000 25.50 46 69.25000 65 319.0000 168.0000
Max. 20.0 150.00000 34.00 56 382.00000 100 1050.0000 886.0000

Trial Group Type

group_type Group_Count
Experimental 110
Active Comparator 46
Placebo Comparator 45
Other 15
NA 7
No Intervention 4

Intervention Model

intervention_model Study_Count
Parallel Assignment 57
Single Group Assignment 25
Crossover Assignment 12
Factorial Assignment 2
Sequential Assignment 1
NA 1

Primary Purpose

primary_purpose Study_Count
Treatment 89
Basic Science 3
Supportive Care 3
NA 2
Other 1

Observational Studies

Studies by Country

Country Study_Count
United States 7
NA 5
Thailand 4
Germany 3
Korea, Republic of 2
Belgium 1
China 1
France 1
Hong Kong 1
Israel 1
Switzerland 1
Taiwan 1
Turkey 1
United Kingdom 1

Sites per Study

Site_count Study_Count
1 27
2 2
21 1

Enrollment Metrics

Measure Observational
Min 1.0000
1st Qu 57.0000
Median 135.0000
Mean 469.2414
3rd Qu 400.0000
Max 3011.0000

Observation Model

observational_model Study_Count
Cohort 9
NA 5
Case-Only 4
Ecologic or Community 4
Case-Control 3
Case Control 2
Other 2
Family-Based 1

Time Perspective

time_perspective Study_Count
Prospective 21
Cross-Sectional 5
NA 2
Other 1
Retrospective 1

Registries

Studies by Country

Country Study_Count
Argentina|Brazil|Colombia|Costa Rica|Dominican Republic|Guatemala|Honduras|Panama|Peru 1
Germany 1
Korea, Republic of 1
Thailand 1

Sites per Study

Site_count Study_Count
1 3
31 1

Enrollment Metrics

Measure Registries
Min 110.00
1st Qu 192.50
Median 358.50
Mean 331.75
3rd Qu 497.75
Max 500.00

Registry Model

observational_model Study_Count
Cohort 2
Case-Control 1
Ecologic or Community 1

Time Perspective

time_perspective Study_Count
Prospective 3
Cross-Sectional 1

Follow-up

target_duration Study_Count
1 Day 1
2 Years 1
24 Months 1
4 Weeks 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT04159701 A Study of LY3454738 in Adults With Chronic Spontaneous Urticaria https://ClinicalTrials.gov/show/NCT04159701 Recruiting Eli Lilly and Company 2021-03-03
NCT03580369 A Phase III Study of Efficacy and Safety of Ligelizumab in the Treatment of CSU in Adolescents and Adults Inadequately Controlled With H1-antihistamines https://ClinicalTrials.gov/show/NCT03580369 Recruiting Novartis 2021-01-28
NCT03580356 A Phase III Study of Efficacy and Safety of Ligelizumab in the Treatment of CSU in Adolescents and Adults Inadequately Controlled With H1-antihistamines. https://ClinicalTrials.gov/show/NCT03580356 Recruiting Novartis 2021-04-09
NCT03328897 Study of Efficacy and Safety of Xolair® (Omalizumab) in Chinese Patients With Chronic Spontaneous Urticaria https://ClinicalTrials.gov/show/NCT03328897 Completed Novartis 2019-07-23
NCT03296358 Adding a Short Burst of Corticosteroid to the Conventional Treatment of H1 Antihistamines in Emergency Department. https://ClinicalTrials.gov/show/NCT03296358 Completed Chulalongkorn University 2019-10-31
NCT03250143 To Assess and Compare the Efficacy of Cyclosporine Versus Azathioprine in the Treatment of Chronic Refractory Urticaria https://ClinicalTrials.gov/show/NCT03250143 Completed Postgraduate Institute of Medical Education and Research 2017-11-30
NCT03183024 Treatment of Chronic Urticarial Unresponsive to H1-antihistamines With an Anti-IL5Ralpha Monoclonal Antibody https://ClinicalTrials.gov/show/NCT03183024 Completed Bernstein Clinical Research Center 2018-11-06
NCT03137069 Efficacy and Safety of GDC-0853 in Participants With Refractory Chronic Spontaneous Urticaria (CSU) https://ClinicalTrials.gov/show/NCT03137069 Completed Genentech, Inc. 2019-09-27
NCT03111628 Role of Immunoglobulin E (IgE) Bearing Cells in Chronic Idiopathic Urticaria (CIU) https://ClinicalTrials.gov/show/NCT03111628 Completed Johns Hopkins University 2020-05-01
NCT02935699 Clinical Trial Comparing JDP-205 to Diphenhydramine Injection for the Treatment of Acute Urticaria https://ClinicalTrials.gov/show/NCT02935699 Completed JDP Therapeutics, Inc. 2018-04-30
NCT02892682 The Role of the Coagulation Pathways in Recurrent Angioedema https://ClinicalTrials.gov/show/NCT02892682 Recruiting University Hospital, Montpellier 2021-05-31
NCT02824393 Experimental Autologous Mesenchymal Stem Cell Therapy in Treatment of Chronic Autoimmune Urticaria https://ClinicalTrials.gov/show/NCT02824393 Completed Celal Bayar University 2018-05-15
NCT02814630 Three-month, Single-center Study to Identify Biomarkers/Response to Xolair Therapy in Chronic Idiopathic Urticaria https://ClinicalTrials.gov/show/NCT02814630 Completed Asthma Inc Clinical Research Center 2018-11-02
NCT02649218 A Safety Extension Study to Evaluate the Long-term Safety of QGE031 in Chronic Spontaneous Urticaria (CSU) Patients https://ClinicalTrials.gov/show/NCT02649218 Completed Novartis 2019-05-02
NCT02576041 Effects of Bilastine on F1 Simulator Driving Performance in Patients Affected by Allergic Rhinitis and/or Urticaria https://ClinicalTrials.gov/show/NCT02576041 Completed Menarini International Operations Luxembourg SA 2015-12-31
NCT02565680 Glucocorticoids With Antihistamines Versus Antihistamines in Acute Urticaria in Emergency https://ClinicalTrials.gov/show/NCT02565680 Completed University Hospital, Toulouse 2014-02-28
NCT02550106 Omalizumab in Chronic Spontaneous Urticaria Patients Non Responding to Initial Standard antihistaminE Treatment https://ClinicalTrials.gov/show/NCT02550106 Completed Novartis 2016-01-11
NCT02477332 Dose-finding Study of QGE031 as add-on Therapy to Evaluate Efficacy and Safety in Patients With CSU https://ClinicalTrials.gov/show/NCT02477332 Completed Novartis 2016-11-02
NCT02424799 Study to Investigate Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of GSK2646264 https://ClinicalTrials.gov/show/NCT02424799 Completed GlaxoSmithKline 2017-11-10
NCT02392624 A Study of the Efficacy and Safety of Omalizumab Through 48 Weeks in Participants With Chronic Idiopathic Urticaria https://ClinicalTrials.gov/show/NCT02392624 Completed Genentech, Inc. 2017-03-09
NCT02372604 Efficacy of Levocetirizine Fourfold Dosage in Chronic Spontaneous Urticaria https://ClinicalTrials.gov/show/NCT02372604 Completed Hospices Civils de Lyon 2016-12-31
NCT02329223 Study of Efficacy and Safety of Omalizumab in Refractory Chronic Spontaneous Urticaria Patients https://ClinicalTrials.gov/show/NCT02329223 Completed Novartis 2015-12-31
NCT02262130 Omalizumab in Severe and Refractory Solar Urticaria https://ClinicalTrials.gov/show/NCT02262130 Completed Centre Hospitalier Universitaire de Besancon 2015-09-29
NCT02213367 Bilastine Updosing in Chronic Spontaneous Urticaria https://ClinicalTrials.gov/show/NCT02213367 Completed Charite University, Berlin, Germany 2016-03-31
NCT02171416 Cold Contact Urticaria Treatment With Rilonacept https://ClinicalTrials.gov/show/NCT02171416 Completed Charite University, Berlin, Germany 2018-02-28
NCT02169115 Urticaria Facticia Treatment With Omalizumab (UFO) https://ClinicalTrials.gov/show/NCT02169115 Completed Charite University, Berlin, Germany 2014-12-31
NCT02161562 OPTIMA: Efficacy of Optimized Re-treatment and Step-up Therapy With Omalizumab in Chronic Spontaneous Urticaria (CSU) Patients https://ClinicalTrials.gov/show/NCT02161562 Completed Novartis 2016-11-03
NCT01292473 A Study to Evaluate the Efficacy, Response Duration and Safety of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU)/Chronic Spontaneous Urticaria (CSU) Who Remain Symptomatic Despite Antihistamine Treatment (H1) https://ClinicalTrials.gov/show/NCT01292473 Completed Genentech, Inc. 2012-06-30
NCT01287117 A Study of the Efficacy and Safety of Omalizumab (Xolair) in Patients With Chronic Idiopathic Urticaria (CIU)/Chronic Spontaneous Urticaria (CSU) Who Remain Symptomatic Despite Antihistamine (H1) Treatment https://ClinicalTrials.gov/show/NCT01287117 Completed Genentech, Inc. 2012-10-31
NCT01271075 Bilastine Updosing - Characterization of Underlying Mechanisms https://ClinicalTrials.gov/show/NCT01271075 Completed Charite University, Berlin, Germany 2011-08-31
NCT02023164 Multicenter Pilot Phase III Clinical Trials of JDP-205 iv Injection for the Treatment of Acute Urticaria Associated With an Acute Allergic Reaction. https://ClinicalTrials.gov/show/NCT02023164 Completed JDP Therapeutics, Inc. 2014-12-31
NCT02045524 A Pilot Single Dose Crossover Pharmacokinetics Study Of JDP-205 Injection, 10 mg, In Healthy Male And Female Volunteers https://ClinicalTrials.gov/show/NCT02045524 Completed JDP Therapeutics, Inc. 2011-09-30
NCT02031679 Efficacy and Safety of Chemoattractant Receptor-homologous Molecule Expressed on T Helper Type 2 (CRTh2) Antagonist AZD1981 in Chronic Idiopathic Urticaria (CIU) Antihistamines https://ClinicalTrials.gov/show/NCT02031679 Completed Johns Hopkins University 2016-01-31
NCT02012387 Efficacy Study of Omalizumab in Cholinergic Urticaria https://ClinicalTrials.gov/show/NCT02012387 Completed Clinica Universidad de Navarra, Universidad de Navarra 2016-09-30
NCT01987947 A Study of Quilizumab Versus Placebo in Patients With Refractory Chronic Spontaneous Urticaria https://ClinicalTrials.gov/show/NCT01987947 Completed Genentech, Inc. 2014-10-31
NCT01940393 Evaluation of the Inhibitory Effect of 5 Anti-Histamines in Urticaria https://ClinicalTrials.gov/show/NCT01940393 Completed Grupo de Alergología Clínica y Experimental 2013-12-31
NCT01916967 An Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Chronic Urticaria (MK-4117-201) https://ClinicalTrials.gov/show/NCT01916967 Completed Merck Sharp & Dohme Corp. 2014-02-28
NCT01897428 PK Comparisons of Bepotastine Besilate 10 mg and Bepotastine Salicylate 9.64 mg https://ClinicalTrials.gov/show/NCT01897428 Completed Korea University Anam Hospital 2011-05-31
NCT01803763 Prospective Double-blind Placebo-controlled Study of the Effect of Xolair (Omalizumab) in Chronic Urticaria Patients https://ClinicalTrials.gov/show/NCT01803763 Completed University Hospital Inselspital, Berne 2014-03-31
NCT01723072 Impact of Omalizumab on Quality of Life Measures and Angioedema Occurrence in Patients With CSU Refractory to Therapy https://ClinicalTrials.gov/show/NCT01723072 Completed Novartis 2014-05-31
NCT01715740 Study of the Effects of Chinese Herbal Medicine on Chronic Urticaria https://ClinicalTrials.gov/show/NCT01715740 Completed Chang Gung Memorial Hospital 2015-08-31
NCT01713725 Efficacy and Safety Study of Omalizumab (Xolair®) to Treat Chronic Urticaria https://ClinicalTrials.gov/show/NCT01713725 Completed Clinica Universidad de Navarra, Universidad de Navarra 2016-02-29
NCT01701583 Effect of Omalizumab (Xolair) on Basophils in Patients With Chronic Idiopathic Urticaria https://ClinicalTrials.gov/show/NCT01701583 Completed University of Colorado, Denver 2016-04-30
NCT01605487 Study to Assess Efficacy, Safety and Mechanism of Rupatadine in Cold Urticaria https://ClinicalTrials.gov/show/NCT01605487 Completed Charite University, Berlin, Germany 2013-09-30
NCT01599637 Mode of Action Study of Omalizumab in Patients With Chronic Idiopathic Urticaria (CIU) Who Fail to Respond to Antihistamine Treatment https://ClinicalTrials.gov/show/NCT01599637 Completed Novartis 2013-09-30
NCT01586091 Safety Study of Levocetirizine and Fexofenadine https://ClinicalTrials.gov/show/NCT01586091 Completed Charite University, Berlin, Germany 2011-11-30
NCT01580592 Cold Urticaria Treatment With Xolair https://ClinicalTrials.gov/show/NCT01580592 Completed Charite University, Berlin, Germany 2014-12-31
NCT02024152 Safety, Tolerability and Pharmacokinetics Trial of JDP-205 Injection 10 mg https://ClinicalTrials.gov/show/NCT02024152 Completed JDP Therapeutics, Inc. 2011-07-31
NCT01444196 Desloratadine 5, 10 and 20mg in Patients With Cold Urticaria https://ClinicalTrials.gov/show/NCT01444196 Completed Charite University, Berlin, Germany 2010-04-30
NCT01371877 The Role of Vitamin D in Chronic Urticaria and Angioedema Treatment https://ClinicalTrials.gov/show/NCT01371877 Completed University of Nebraska 2013-09-30
NCT01360658 Intravenous Immunoglobulins in Severe and Refractory Solar Urticaria https://ClinicalTrials.gov/show/NCT01360658 Completed Centre Hospitalier Universitaire de Besancon 2013-06-30
NCT04439955 Study to Evaluate the Safety, Tolerability and Efficacy of Cannabidiol (CBD) as a Steroid-sparing Therapy in Chronic Spontaneous Urticaria (CSU) Patients https://ClinicalTrials.gov/show/NCT04439955 Recruiting Stero Biotechs Ltd. 2020-12-30
NCT04210843 Study of Efficacy and Safety of Ligelizumab in Chronic Spontaneous Urticaria Patients Who Completed a Previous Study With Ligelizumab https://ClinicalTrials.gov/show/NCT04210843 Recruiting Novartis 2022-02-07
NCT04210323 Shotblocker® Use in Subcutaneous Injection https://ClinicalTrials.gov/show/NCT04210323 Completed Saglik Bilimleri Universitesi 2018-06-05
NCT03991845 A Trial to Evaluate the Effect of Vitamin D Supplementation in Patients With Chronic Urticaria https://ClinicalTrials.gov/show/NCT03991845 Enrolling by invitation Postgraduate Institute of Medical Education and Research 2019-11-27
NCT03926611 Dose-finding Study to Evaluate Efficacy and Safety of LOU064 in Patients With CSU Inadequately Controlled by H1-antihistamines https://ClinicalTrials.gov/show/NCT03926611 Recruiting Novartis 2020-08-17
NCT03907878 A Safety and Efficacy Study of Ligelizumab in the Treatment of CSU in Japanese Patients Inadequately Controlled With H1- Antihistamines https://ClinicalTrials.gov/show/NCT03907878 Recruiting Novartis 2021-10-18
NCT03858634 A Study to Assess the Efficacy, Safety and Tolerability of KPL-716 in Reducing Pruritus in Chronic Pruritic Diseases https://ClinicalTrials.gov/show/NCT03858634 Active, not recruiting Kiniksa Pharmaceuticals, Ltd. 2020-06-30
NCT03789422 Tranexamic Acid and Spontaneous Chronic Urticaria https://ClinicalTrials.gov/show/NCT03789422 Recruiting University Hospital, Grenoble 2021-01-31
NCT03749148 Cholinergic Urticaria - Efficacy of Dupilumab https://ClinicalTrials.gov/show/NCT03749148 Recruiting Charite University, Berlin, Germany 2020-10-31
NCT03749135 Dupilumab in Chronic Spontaneous Urticaria https://ClinicalTrials.gov/show/NCT03749135 Recruiting Charite University, Berlin, Germany 2020-10-31
NCT03693625 A Study to Evaluate the Long-term Safety and Efficacy of Fenebrutinib in Participants Previously Enrolled in a Fenebrutinib Chronic Spontaneous Urticaria (CSU) Study https://ClinicalTrials.gov/show/NCT03693625 Completed Genentech, Inc. 2019-10-23
NCT03632291 Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of UB-221 as an Add-on Therapy in CSU Patients https://ClinicalTrials.gov/show/NCT03632291 Recruiting United BioPharma 2021-12-31
NCT03545464 COrticosteroids in acUte uRticAria in emerGency dEpartment https://ClinicalTrials.gov/show/NCT03545464 Recruiting Assistance Publique - Hôpitaux de Paris 2020-11-15
NCT03494881 Mepolizumab for the Treatment of Chronic Spontaneous Urticaria https://ClinicalTrials.gov/show/NCT03494881 Recruiting Mayo Clinic 2021-03-15
NCT03437278 Study to Investigate the Efficacy and Safety of QGE031 in Adolescent Patients With Chronic Spontaneous Urticaria (CSU) https://ClinicalTrials.gov/show/NCT03437278 Recruiting Novartis 2021-02-26
NCT03436797 A Study to Assess the Efficacy and Safety of AK002 in Subjects With Antihistamine-Resistant Chronic Urticaria https://ClinicalTrials.gov/show/NCT03436797 Completed Allakos, Inc. 2018-11-21
NCT01264939 A Safety Study of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU) Who Remain Symptomatic Despite Treatment With H1 Antihistamines, H2 Blockers, and/or Leukotriene Receptor Antagonists https://ClinicalTrials.gov/show/NCT01264939 Completed Genentech, Inc. 2012-11-30
NCT01250652 Levocetirizine Plus Bed-Time Hydroxyzine in the Management of Corticodependent Chronic Urticaria Versus Levocetirizine Alone in High Doses https://ClinicalTrials.gov/show/NCT01250652 Completed Association Asthma, Bulgaria 2013-02-28
NCT01170936 Ilaris® in Urticarial Vasculitis - Investigation of Treatment Responses https://ClinicalTrials.gov/show/NCT01170936 Completed Charite University, Berlin, Germany 2011-09-30
NCT01081574 Pharmacokinetic Study of Bilastine in Children From 2 to < 12 Years of Age With Either Allergic Rhinoconjunctivitis (AR) or Chronic Urticaria (CU) https://ClinicalTrials.gov/show/NCT01081574 Completed Faes Farma, S.A. 2012-06-30
NCT00886795 Safety and Efficacy of Abatacept in Subjects With Chronic Urticaria Who Have Had an Inadequate Response to Anti-histamine Therapy https://ClinicalTrials.gov/show/NCT00886795 Completed Johns Hopkins University 2013-03-31
NCT00866788 A Study of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU) Who Remain Symptomatic With Antihistamine Treatment (H1) https://ClinicalTrials.gov/show/NCT00866788 Completed Genentech, Inc. 2010-01-31
NCT00859534 Phase II Solar Urticaria (SU) Pilot Study https://ClinicalTrials.gov/show/NCT00859534 Completed Clinuvel Pharmaceuticals Limited 2009-06-30
NCT04180488 Dupilumab for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine and Who Are naïve to, Intolerant of, or Incomplete Responders to Omalizumab https://ClinicalTrials.gov/show/NCT04180488 Recruiting Sanofi 2021-07-31
NCT04109313 Open-label, Multicenter, Extension Study to Evaluate Long-term Safety and Tolerability of LOU064 in Subjects With CSU https://ClinicalTrials.gov/show/NCT04109313 Recruiting Novartis 2020-05-12
NCT01111136 Stress Intervention for Chronic Urticaria https://ClinicalTrials.gov/show/NCT01111136 Completed University of Mississippi Medical Center 2010-07-31
NCT00783354 A Comparison of Aerius Continuous Treatment Versus Aerius PRN for Chronic Idiopathic Urticaria (Study P03147) https://ClinicalTrials.gov/show/NCT00783354 Completed Merck Sharp & Dohme Corp. 2004-02-01
NCT00757562 Safety of Desloratadine in Children With Allergy Sensitivity and Chronic Hives, Who Are Poor Metabolizers of Desloratadine (Study P02994) https://ClinicalTrials.gov/show/NCT00757562 Completed Merck Sharp & Dohme Corp. 2003-10-01
NCT00751218 A Comparative Double-Blind, Double- Dummy Study of Desloratadine (DL) 5 MG Once Daily, Cetirizine 10 MG Once Daily, and Placebo Once Daily in Patients With Chronic Idiopathic Urticaria (Study P03735) https://ClinicalTrials.gov/show/NCT00751218 Completed Merck Sharp & Dohme Corp. 2005-05-24
NCT00628108 Safety Study of Levocetirizine Dihydrochloride Oral Liquid Formulation in Children Aged 6 Months to 11 Months https://ClinicalTrials.gov/show/NCT00628108 Completed UCB Pharma 2008-09-30
NCT00619801 Safety Study of Levocetirizine Dihydrochloride Oral Liquid Formulation in Children Aged 1 to Less Than 6 Years Suffering From Allergic Rhinitis or Chronic Urticaria of Unknown Origin https://ClinicalTrials.gov/show/NCT00619801 Completed UCB Pharma 2008-07-31
NCT00600847 A Study to Assess and Compare the Effects of 5 mg vs. 20 mg Desloratadine on the Development of Cold Urticaria Lesions https://ClinicalTrials.gov/show/NCT00600847 Completed Charite University, Berlin, Germany 2007-11-30
NCT00598611 Effects of 5 mg vs. 20 mg Desloratadine on Skin Lesions in Patients With Chronic Urticaria (CU) https://ClinicalTrials.gov/show/NCT00598611 Completed Charite University, Berlin, Germany 2009-08-31
NCT00536380 Study for the Treatment of Chronic Idiopathic Urticaria With High Doses of AERIUS (Desloratadine) (Study P04849) https://ClinicalTrials.gov/show/NCT00536380 Completed Merck Sharp & Dohme Corp. 2009-04-30
NCT00525382 Study to Compare the Efficacy and Safety Between Levocetirizine and Loratadine for Chronic Idiopathic Urticaria https://ClinicalTrials.gov/show/NCT00525382 Completed UCB Pharma 2004-03-31
NCT00483496 Evaluation of the Protection Activity of Microfine Titanium Dioxide (Ti02), Pigmentary Ti02 and Bisoctrizole and Their Combinations in Voluntary Patients With Idiopathic Solar Urticaria (SU) https://ClinicalTrials.gov/show/NCT00483496 Completed Orfagen 2008-04-30
NCT00421109 Efficacy Study for the Symptomatic Treatment of Chronic Idiopathic Urticaria https://ClinicalTrials.gov/show/NCT00421109 Completed Faes Farma, S.A. 2007-07-31
NCT00385372 Significance of an Elimination and Provocation Diet in Patients With Chronic Urticaria https://ClinicalTrials.gov/show/NCT00385372 Completed University Hospital Muenster 2007-01-31
NCT00368823 A Trial of Point of Care Information in Ambulatory Pediatrics https://ClinicalTrials.gov/show/NCT00368823 Completed University of Washington NA
NCT00264303 CUTE (Chronic Urticaria Treatment Evaluation) https://ClinicalTrials.gov/show/NCT00264303 Completed UCB Pharma 2007-01-31
NCT00214851 The Use of Kineret (Anakinra) in the Treatment of Familial Cold Urticaria https://ClinicalTrials.gov/show/NCT00214851 Completed Nova Scotia Health Authority 2005-12-31
NCT01960283 Methotrexate in the Treatment of Chronic Idiopathic Urticaria https://ClinicalTrials.gov/show/NCT01960283 Completed University Hospital, Tours 2016-03-31
NCT00130234 Effect of Anti-IgE in Chronic Urticaria https://ClinicalTrials.gov/show/NCT00130234 Completed Johns Hopkins University 2007-09-30
NCT00795522 An Open-Label Study of the Effects of Desloratadine (Aerius.) Treatment on the Quality of Life of Patients With Chronic Idiopathic Urticaria (Study P02540) https://ClinicalTrials.gov/show/NCT00795522 Completed Merck Sharp & Dohme Corp. 2005-02-28
NCT00795158 How Desloratadine (Clarinex, Aerius) Affects Quality of Life in Patients With Chronic Idiopathic Urticaria (Have Had Hives for 6 Weeks or Longer)(Study P02988) https://ClinicalTrials.gov/show/NCT00795158 Completed Merck Sharp & Dohme Corp. 2004-01-31
NCT00481676 Efficacy and Safety of Omalizumab in Adults (18-70 Years) With Moderate to Severe Chronic Urticaria https://ClinicalTrials.gov/show/NCT00481676 Completed Novartis 2009-04-30
NCT00288704 Rilonacept for Treatment of Cryopyrin-Associated Periodic Syndromes (CAPS) https://ClinicalTrials.gov/show/NCT00288704 Completed Regeneron Pharmaceuticals 2008-06-30

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03406325 Mast Cell Activation Test in Allergic Disease https://ClinicalTrials.gov/show/NCT03406325 Completed Hong Kong Sanatorium & Hospital 2019-12-01
NCT03151902 Detection of Viral Particels in Urticaria Patients https://ClinicalTrials.gov/show/NCT03151902 Recruiting HaEmek Medical Center, Israel 2018-12-31
NCT03101618 Animal Allergy in Korean Pet Owners, Pet-related Industry Workers, and Laboratory Animal Reseachers https://ClinicalTrials.gov/show/NCT03101618 Completed Gachon University Gil Medical Center 2016-11-27
NCT02866864 Animal Allergy in Korean Veterinary Researcher https://ClinicalTrials.gov/show/NCT02866864 Completed Gachon University Gil Medical Center 2016-08-26
NCT02761473 Cutaneous Mastocytosis in Children: Analysis of Somatic and Germline Mutations https://ClinicalTrials.gov/show/NCT02761473 Active, not recruiting University of Minnesota 2020-05-01
NCT02671006 Monitoring Chronic Urticaria Basophil Irritability by Cytometry https://ClinicalTrials.gov/show/NCT02671006 Completed Centre Hospitalier Universitaire de Saint Etienne 2017-08-31
NCT02435238 AWARE - Chronic Urticaria https://ClinicalTrials.gov/show/NCT02435238 Completed Novartis 2017-09-27
NCT02285049 Cross-Cultural of the Validity, Reliability and Interpretability of Thai-version of Urticaria Control Test https://ClinicalTrials.gov/show/NCT02285049 Completed Mahidol University 2015-02-28
NCT02285023 The Validity, Reliability and Interpretability of Thai-version of Chronic Urticaria Quality of Life Questionnaire https://ClinicalTrials.gov/show/NCT02285023 Completed Mahidol University 2015-02-28
NCT02238249 Study to Investigate the Safety and Efficacy of Alesion® in Japanese Paediatric Patients With Urticaria https://ClinicalTrials.gov/show/NCT02238249 Completed Boehringer Ingelheim 2007-09-30
NCT01284426 Natural History of Chronic Urticaria https://ClinicalTrials.gov/show/NCT01284426 Completed Mahidol University 2009-03-31
NCT01637116 Profiling Urticaria for the Identification of Subtypes https://ClinicalTrials.gov/show/NCT01637116 Completed Charite University, Berlin, Germany 2015-06-30
NCT01610128 Development of an Urticaria Control Test https://ClinicalTrials.gov/show/NCT01610128 Completed Charite University, Berlin, Germany 2013-06-30
NCT01614834 Validation of an Urticaria Control Test https://ClinicalTrials.gov/show/NCT01614834 Completed Charite University, Berlin, Germany 2013-08-31
NCT04314999 Frequency of Parasite Infestation in Patients With Chronic Spontaneous Urticaria https://ClinicalTrials.gov/show/NCT04314999 Completed University Hospital, Basel, Switzerland 2019-09-30
NCT03849625 Characteristics of Patients Diagnosed With NSAID Sensitivity in Thailand https://ClinicalTrials.gov/show/NCT03849625 Recruiting Chulalongkorn University 2020-06-30
NCT03656939 A Safety Study For Prevenar 13 Among Chinese Children https://ClinicalTrials.gov/show/NCT03656939 Active, not recruiting Pfizer 2020-09-30
NCT03443362 Role of Endothelial Cells in the Pathogenesis of Chronic Urticaria. https://ClinicalTrials.gov/show/NCT03443362 Recruiting Brugmann University Hospital 2020-12-31
NCT01091402 Autologous Serum Skin Test and Serum IL-18 Levels in Chronic Idiopathic Urticaria and Respiratory Allergic Diseases https://ClinicalTrials.gov/show/NCT01091402 Completed Eskisehir Osmangazi University NA
NCT00887939 Pathogenesis of Physical Induced Urticarial Syndromes https://ClinicalTrials.gov/show/NCT00887939 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT00876369 Vitamin D Levels in Subjects With Chronic Urticaria and Angioedema https://ClinicalTrials.gov/show/NCT00876369 Completed University of Nebraska 2009-12-31
NCT00868036 Evaluating for Contact Allergies in Patients With Chronic Urticaria https://ClinicalTrials.gov/show/NCT00868036 Completed Tufts Medical Center 2010-12-31
NCT00852943 Screening Protocol for Genetic Diseases of Allergic Inflammation https://ClinicalTrials.gov/show/NCT00852943 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT00762983 Observation of Use of Claritin (Loratadine) Tablet, RediTabs, and Dry Syrup in Children (Study P05834)(COMPLETED) https://ClinicalTrials.gov/show/NCT00762983 Completed Merck Sharp & Dohme Corp. 2009-02-28
NCT00737451 Association of Thyroid Autoimmunity and Chronic Urticaria https://ClinicalTrials.gov/show/NCT00737451 Completed Far Eastern Memorial Hospital 2010-11-30
NCT00724698 Evaluation of Desloratadine When Used in Patients With Either Allergic Rhinitis or Chronic Idiopathic Urticaria https://ClinicalTrials.gov/show/NCT00724698 Completed Merck Sharp & Dohme Corp. 2007-12-31
NCT00723736 Safety of Aerius Syrup in Pediatric Patients Aged 1-5 Years Old With Allergic Rhinitis or Chronic Idiopathic Urticaria (Study P04446AM1)(COMPLETED) https://ClinicalTrials.gov/show/NCT00723736 Completed Merck Sharp & Dohme Corp. 2008-06-30
NCT00761527 Observation of Side Effects and Effectiveness of Desloratadine (Aerius) Syrup in Filipino Children (Study P05634) https://ClinicalTrials.gov/show/NCT00761527 Completed Merck Sharp & Dohme Corp. 2010-05-31
NCT00467792 Natural History of Urticaria Pigmentosa in Children https://ClinicalTrials.gov/show/NCT00467792 Completed Medical College of Wisconsin 2008-06-30
NCT00001150 Induction of Suction Blisters in Patients With Urticaria, Blistering Diseases, Inflammatory Dermatoses and Neoplastic Disorders, and in Normal Volunteers https://ClinicalTrials.gov/show/NCT00001150 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03324919 Patient Centered Care Situation and Health-related Quality of Life by Patients With Psoriasis, Urticaria or Lupus https://ClinicalTrials.gov/show/NCT03324919 Completed University Hospital Regensburg 2017-04-30
NCT03293225 Efficacy of Antihistamine Dosing-up and add-on Treatment With H2-receptor Antagonist https://ClinicalTrials.gov/show/NCT03293225 Completed Ajou University School of Medicine 2019-05-24
NCT02626221 A Worldwide Antihistamine-Refractory Chronic Urticaria Patient Evaluation in Latin America and Canada (AWARE-LACan) https://ClinicalTrials.gov/show/NCT02626221 Completed Novartis 2018-03-21
NCT02000648 Real-life Management and Therapeutic Outcome of Patients With Chronic Rhinitis and Chronic Urticaria in Thailand https://ClinicalTrials.gov/show/NCT02000648 Completed Chulalongkorn University 2015-02-28